Massachusetts AFL-CIO Scholarship Practice Exam

The Female Labor Reform Association was established by Lowell factory girls in the early 19th century as a response to the challenging working conditions they faced in the textile mills. This organization was significant because it represented one of the first formal attempts by women to organize for better working conditions, shorter hours, and fair wages. The Lowell factory girls were instrumental in advocating for labor reforms, drawing attention to the injustices and hardships linked to their labor-intensive jobs. Their efforts laid the groundwork for future labor movements and women's rights activism, marking an important step in the history of labor rights in the United States.

The other organizations listed, while they may address similar themes related to labor or women's rights, do not specifically trace their origins directly to the Lowell factory girls. Therefore, the Female Labor Reform Association stands out as the correct answer in this context.